What is Osteogenesis Imperfecta?

The Osteogenesis Imperfecta (OI) refers to an illness of genetic bone disorder. People who suffer from OI are born with defective connective tissue, or without the ability to make it.


Interesting facts about Osteogenesis Imperfecta!

  • A person with a form of OI caused by mutation has a 50% chance of passing the disorder to his or her children.
  • Teeth brittleness is a symptom of OI, so Dental problems can happen.
  • If parents have one child with OI, there is a 25% chance of their next child having OI.
  • An Egyptian mummy from 1000 BC had OI.  
  • Prince Ivan, from the ninth century, suffered from OI and according to legend, he was carried into battle on a shield because his legs were too soft.
  • In the United States, 1 in 20,000 births have OI.  


Famous people with Osteogenesis Imperfecta



American actor Michael J. Anderson 



British actress Julie Fernandez 


Jazz pianist Michel Petrucciani 



Nabil Shaban


Web by Stanley Wang from Yew Chung International School HK